BDBM50249958 CHEMBL489520::[2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 4-(4-[2-(4-Methylphenyl)ethynyl]phenoxy)butanoate

SMILES [#6]\[#6](-[#6])=[#6]-1/[#6]C([#6]-[#8])([#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]-[#8]-c2ccc(cc2)C#Cc2ccc(-[#6])cc2)[#8]-[#6]-1=O

InChI Key InChIKey=XUTMONHBGYHWES-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50249958   

TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50249958(CHEMBL489520 | [2-(Hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed