BDBM50250161 CHEMBL4071820
SMILES COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(cc3)-c3cnco3)c(=O)[nH]c2=O)ccc1F
InChI Key InChIKey=XHWPSFKZEOYPJH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50250161
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetStromelysin-2(Homo sapiens (Human))
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP10 (unknown origin) assessed using (5-FAM/QX) FRET peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Zhaw Zurich University of Applied Sciences
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of C-terminal tagged human recombinant MMP13 catalytic domain expressed in Escherichia coli using (5-FAM/QX) FRET peptide as substrate by ...More data for this Ligand-Target Pair