BDBM50251389 (R)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)-N-(thiazol-2-yl)propanamide::CHEMBL517534

SMILES O=C(Nc1nccs1)[C@H](CC1CCOCC1)c1ccc(cc1)S(=O)(=O)C1CC1

InChI Key InChIKey=DOTNXOZFPLAGNY-GOSISDBHSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251389   

TargetHexokinase-4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50251389((R)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydr...)
Affinity DataEC50:  570nMAssay Description:Activation of human glucokinase expressed in Escherichia coli BL21(DE3) coexpressing G6PDH by spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50251389((R)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydr...)
Affinity DataEC50:  570nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed