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BDBM50251645 CHEMBL479763::N-(6-(pyridin-2-ylmethoxy)pyridin-3-yl)-1H-indole-3-carboxamide

SMILES: O=C(Nc1ccc(OCc2ccccn2)nc1)c1c[nH]c2ccccc12

InChI Key: InChIKey=UWUOMRXMLVBUOG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251645   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50251645
PNG
(CHEMBL479763 | N-(6-(pyridin-2-ylmethoxy)pyridin-3...)
Show SMILES O=C(Nc1ccc(OCc2ccccn2)nc1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C20H16N4O2/c25-20(17-12-22-18-7-2-1-6-16(17)18)24-14-8-9-19(23-11-14)26-13-15-5-3-4-10-21-15/h1-12,22H,13H2,(H,24,25)
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PC sid
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Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine at human cloned 5HT2C receptor expressed in CHOK1 cell


Bioorg Med Chem Lett 18: 3844-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.064
BindingDB Entry DOI: 10.7270/Q2P84BQN
More data for this
Ligand-Target Pair