BDBM50251676 CHEMBL516444::N-(5-chloro-2-methylphenyl)-2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetrahydroquinolin-5-amine

SMILES CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)Nc1cc(Cl)ccc1C

InChI Key InChIKey=FJSNFSDCNQDNOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251676   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50251676(CHEMBL516444 | N-(5-chloro-2-methylphenyl)-2-(2,6-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed