BDBM50252219 8-{4-[(1,4-cis)-4-(5-Fluoro-1H-indol-3-yl)-cyclohexyl]-piperazin-1-yl}-quinoline::CHEMBL481747

SMILES Fc1ccc2[nH]cc([C@@H]3CC[C@@H](CC3)N3CCN(CC3)c3cccc4cccnc34)c2c1

InChI Key InChIKey=KYRUDMLLMDKVOX-IQGASKDCSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252219   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252219(8-{4-[(1,4-cis)-4-(5-Fluoro-1H-indol-3-yl)-cyclohe...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252219(8-{4-[(1,4-cis)-4-(5-Fluoro-1H-indol-3-yl)-cyclohe...)
Affinity DataKi:  69.7nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed