BDBM50252920 (S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno[3,4-d]pyrimidin-2,4(1H,3H)-dione::CHEMBL492469
SMILES N[C@@H](Cn1c2CSCc2c(=O)[nH]c1=O)C(O)=O
InChI Key InChIKey=PETHBUJXGHVGGK-YFKPBYRVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50252920
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Displacement of [3H]AMPA from rat GluA2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 288nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 311nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 3.25E+3nMAssay Description:Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]SYM2081 from rat GluK2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 2.42E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR4 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electro...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human iGluR5(Q)1b expressed in CHO-K1 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 3.39E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR3 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electro...More data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR2(Q) expressed in Xenopus laevis oocytes by two electrode voltage-clamp elec...More data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 1.18E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized rat recombinant flip iGluR1 expressed in Xenopus laevis oocytes by two electrode voltage-clamp electro...More data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 1.85E+4nMAssay Description:Agonist activity at cyclothiazide-desensitized human flip iGluR1 expressed in CHO-K1 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cellsMore data for this Ligand-Target Pair