BDBM50253005 CHEMBL4076887

SMILES Clc1ccc(cc1Cl)-c1ccc(\C=N\NC(=O)CSc2nnc(Nc3ccccc3)s2)o1

InChI Key InChIKey=GKEXFTYZBKRSDO-BHGWPJFGSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253005   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50253005(CHEMBL4076887)
Affinity DataKi:  0.690nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50253005(CHEMBL4076887)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of carbonic anhydrase-1 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed