BDBM50253469 1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde guanylhydrazone::2-[(1-chloro-3,4-dihydronaphthalen-2-yl)methylene]hydrazinecarboximidamide::CHEMBL448651

SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Cl)-c2ccccc2-[#6]-[#6]-1

InChI Key InChIKey=OOCGRYVVXPBNID-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50253469   

TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...)
Affinity DataIC50:  5.50E+3nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition of steroid receptor coactivator interaction in african green monkey COS7 cells by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 (isolate BRU/L...)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...)
Affinity DataIC50:  2.50E+7nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alpha/estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnvelope glycoprotein gp70(Mouse mammary tumor virus (strain GR) (MMTV))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha (unknown origin) expressed in human HEC1 cells after 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50253469(1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed