BDBM50253581 2,4-Diamino-6-[N-(2,5-dimethoxybenzyl)-N-ethylamino]quinazoline::CHEMBL521672
SMILES CCN(Cc1cc(OC)ccc1OC)c1ccc2nc(N)nc(N)c2c1
InChI Key InChIKey=ZDKAQGINSFSQDO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50253581
Affinity DataIC50: 9.90nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Inhibition of Mycobacterium avium dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair