BDBM50254365 (+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4'-ethoxy-biphenyl-3-sulfonylamino)-3-oxo-propyl]-benzamidine::CHEMBL518179

SMILES CCOc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1

InChI Key InChIKey=FKQDSIMOEGWTEY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254365   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254365((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  6nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254365((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  150nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254365((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  450nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254365((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  660nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254365((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed