BDBM50254767 CHEMBL464271::N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(2,4-difluorophenylthio)-1H-indol-4-yloxy)acetamide

SMILES Fc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(F)c1

InChI Key InChIKey=YCFSEKSQXAEPEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254767   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254767(CHEMBL464271 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  18.3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254767(CHEMBL464271 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed