BDBM50254880 CHEMBL520741::N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(3,4-dimethoxyphenylthio)-1H-indol-4-yloxy)acetamide

SMILES COc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1OC

InChI Key InChIKey=DUUFBBCUYUGAGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254880   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254880(CHEMBL520741 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  9.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254880(CHEMBL520741 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed