BDBM50255809 4-(((R)-3-(3,4-difluorobenzyl)-2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N-hydroxybenzamide::CHEMBL481018

SMILES ONC(=O)c1ccc(CN2[C@H](Cc3ccc(F)c(F)c3)C(=O)Nc3ccccc23)cc1

InChI Key InChIKey=QKRZDRHJZWTKRQ-OAQYLSRUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255809   

TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255809(4-(((R)-3-(3,4-difluorobenzyl)-2,3-dihydro-2-oxoqu...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255809(4-(((R)-3-(3,4-difluorobenzyl)-2,3-dihydro-2-oxoqu...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255809(4-(((R)-3-(3,4-difluorobenzyl)-2,3-dihydro-2-oxoqu...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed