BDBM50257394 CHEMBL445747::trans-[2-(3-Methylphenyl)cyclopropyl]methylamine Hydrochloride

SMILES Cc1cccc(c1)[C@H]1C[C@@H]1CN

InChI Key InChIKey=PDGGJTWTUULHJG-GHMZBOCLSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50257394   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi:  268nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi:  5.40E+3nMAssay Description:Displacement of [3H]WIN35428 from DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi:  5.44E+3nMAssay Description:Displacement of [3H]citalopram from SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50257394(CHEMBL445747 | trans-[2-(3-Methylphenyl)cyclopropy...)
Affinity DataEC50:  585nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed