BDBM50258423 3-(2-chloro-4-((3-((3,5-dichlorophenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL523368

SMILES CC(C)c1onc(COc2cc(Cl)cc(Cl)c2)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=CIXHUVHQDORPDN-VOTSOKGWSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258423   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258423(3-(2-chloro-4-((3-((3,5-dichlorophenoxy)methyl)-5-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR assessed as SRC1 coactivatior peptide recruitment by cell free FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258423(3-(2-chloro-4-((3-((3,5-dichlorophenoxy)methyl)-5-...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed