BDBM50258639 2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-5-fluorophenyl)oxazole::CHEMBL501404

SMILES Fc1ccc(C2Cc3nccn3C2)c(c1)-c1ncco1

InChI Key InChIKey=BFDKAMOCQFIESP-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258639   

TargetAlpha-2A adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50258639(2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...)
Affinity DataKi: >2.16E+3nMAssay Description:Inhibition of adrenergic alpha2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50258639(2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adrenergic alpha1D receptor expressed in CHO cells assessed as calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50258639(2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50258639(2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human adrenergic alpha1B receptor expressed in CHO cells assessed as calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed