BDBM50259131 CHEMBL466517::JNJ-26990990::N-((Benzo[b]thien-3-yl)methyl)sulfamide::N-(1-benzothien-3-ylmethyl)sulfamide

SMILES: NS(=O)(=O)NCc1csc2ccccc12

InChI Key: InChIKey=AWSKBQNOSRREEY-UHFFFAOYSA-N

Data: 6 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2				J Med Chem 52: 3431-40 (2009) Article DOI: 10.1021/jm900141j BindingDB Entry DOI: 10.7270/Q24F1QMG
					More data for this Ligand-Target Pair
Sodium channel protein type II alpha subunit (Rattus norvegicus)	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of rat Nav1.2 channel expressed in chinese hamster CHL1610 cells at preconditioning pulse of -67 mV after 2 to 3 mins by whole-cell patch-...				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by fluorimetric assay				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of carbonic anhydrase 1				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by CO2 hydration assay				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50259131 (CHEMBL466517 | JNJ-26990990 | N-((Benzo[b]thien-3-...) Show SMILES NS(=O)(=O)NCc1csc2ccccc12 Show InChI InChI=1S/C9H10N2O2S2/c10-15(12,13)11-5-7-6-14-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H2,10,12,13)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of rat Cav2.2 channel expressed in 0.07 Hz frequency-stimulated HEK cells by whole-cell patch-clamp technique				J Med Chem 52: 7528-36 (2009) Article DOI: 10.1021/jm801432r BindingDB Entry DOI: 10.7270/Q21J9BQD
					More data for this Ligand-Target Pair