BDBM50260390 CHEMBL4070683
SMILES CC(C)C[C@H]1C[C@@H](C)[C@@]2(N1C(=O)c1cn(C)cn1)C(=O)Nc1ccc(F)cc21
InChI Key InChIKey=WAFNVKVWBPXGHK-CGSMKXTHSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50260390
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of elF4G-induced full length recombinant human N-terminal His6-SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal His-FLAG-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair