BDBM50260704 3-(2-chlorophenyl)-5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,2,4-triazole::CHEMBL497748

SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key InChIKey=HSVNFDUPXHVBSA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260704   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260704(3-(2-chlorophenyl)-5-(1-(4-chlorophenyl)cyclobutyl...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260704(3-(2-chlorophenyl)-5-(1-(4-chlorophenyl)cyclobutyl...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260704(3-(2-chlorophenyl)-5-(1-(4-chlorophenyl)cyclobutyl...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260704(3-(2-chlorophenyl)-5-(1-(4-chlorophenyl)cyclobutyl...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed