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BDBM50260799 CHEMBL497962::N-hydroxy-2,3-bis(3-(trifluoromethyl)phenylsulfonamido)propanamide

SMILES: ONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=LJLSVOSAAMOXNZ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260799   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-7 (MMP7)


(Homo sapiens (Human))
BDBM50260799
PNG
(CHEMBL497962 | N-hydroxy-2,3-bis(3-(trifluoromethy...)
Show SMILES ONC(=O)C(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)NS(=O)(=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H15F6N3O6S2/c18-16(19,20)10-3-1-5-12(7-10)33(29,30)24-9-14(15(27)25-28)26-34(31,32)13-6-2-4-11(8-13)17(21,22)23/h1-8,14,24,26,28H,9H2,(H,25,27)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
602n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair