BindingDB logo
myBDB logout

BDBM50260800 2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropanamide::CHEMBL496716

SMILES: ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=HKDOGDQOXPWJEG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260800   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Collagenase


(Homo sapiens (Human))
BDBM50260800
PNG
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)
Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.75E+3n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP9


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair
Matrix metalloproteinase 10


(Homo sapiens (Human))
BDBM50260800
PNG
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)
Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.57E+3n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP10


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7)


(Homo sapiens (Human))
BDBM50260800
PNG
(2,3-bis(4-fluorophenylsulfonamido)-N-hydroxypropan...)
Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccc(F)cc1)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C15H15F2N3O6S2/c16-10-1-5-12(6-2-10)27(23,24)18-9-14(15(21)19-22)20-28(25,26)13-7-3-11(17)4-8-13/h1-8,14,18,20,22H,9H2,(H,19,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
625n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair