BindingDB logo
myBDB logout

BDBM50260884 2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxypropanamide::CHEMBL521689

SMILES: COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO

InChI Key: InChIKey=NUJPTPCEVGHZJB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260884   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-7 (MMP7)


(Homo sapiens (Human))
BDBM50260884
PNG
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)
Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO
Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
289n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP7


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (Human))
BDBM50260884
PNG
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)
Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO
Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.24E+5n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP9


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair
Matrix metalloproteinase 10


(Homo sapiens (Human))
BDBM50260884
PNG
(2,3-bis(2,4-dimethoxyphenylsulfonamido)-N-hydroxyp...)
Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1OC)C(=O)NO
Show InChI InChI=1S/C19H25N3O10S2/c1-29-12-5-7-17(15(9-12)31-3)33(25,26)20-11-14(19(23)21-24)22-34(27,28)18-8-6-13(30-2)10-16(18)32-4/h5-10,14,20,22,24H,11H2,1-4H3,(H,21,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.72E+5n/an/an/an/an/an/an/an/a



North Dakota State University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP10


Bioorg Med Chem Lett 18: 3333-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.035
BindingDB Entry DOI: 10.7270/Q2SX6D1R
More data for this
Ligand-Target Pair