BDBM50260911 3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(4-chloro-phenyl)-cyclobutyl]-4-methyl-4H-[1,2,4]triazole::CHEMBL496495

SMILES CCSc1ccccc1-c1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=FOYQEHAQUNUUQI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260911   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260911(3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260911(3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260911(3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260911(3-(3-Chloro-2'-ethylsulfanyl-biphenyl-4-yl)-5-[1-(...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed