BDBM50261631 3-(3-(trifluoromethyl)benzylthio)-5-sec-butyl-4-hydroxy-1H-pyrrol-2(5H)-one::CHEMBL468168::Tetramic acid, 38

SMILES CCC(C)C1NC(=O)C(SCc2cccc(c2)C(F)(F)F)C1=O

InChI Key InChIKey=QGHRPTIBZHSFKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261631   

TargetBeta-secretase 1(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50261631(3-(3-(trifluoromethyl)benzylthio)-5-sec-butyl-4-hy...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50261631(3-(3-(trifluoromethyl)benzylthio)-5-sec-butyl-4-hy...)
Affinity DataIC50:  6.00E+4nMT: 2°CAssay Description:The FRET assay was performed at 20 C on a FLUOstar (BMG Lab Technologies, D-77656 Offenburg) using 96-well microtiter plates (Dynex Microfluor 2, Cha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed