BDBM50261942 6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol::CHEMBL469227

SMILES Oc1cccc(c1)-c1ccc2c(c(O)ccc2c1)-c1ccccc1

InChI Key InChIKey=ZYOIQICRHUXCRL-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50261942   

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  281nMAssay Description:Displacement of [3H]E1 from 17beta-HSD1 in human T47D cells after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]E1 from human placental 17beta-HSD1 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  7.16E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  7.96E+3nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50261942(6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol | CHEMBL46...)
Affinity DataIC50:  540nMAssay Description:Displacement of [3H]E2 from human placental 17beta-HSD2 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed