BDBM50263327 CHEMBL476339::N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine
SMILES Cc1ccnc(Nc2nc(cs2)-c2ccccn2)c1
InChI Key InChIKey=QMEBVRXZLKAAIG-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50263327
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair