BDBM50264071 CHEMBL452409::N-(4-(pyridin-4-yl)thiazol-2-yl)pyridin-2-amine::cid_704533

SMILES N(c1nc(cs1)-c1ccncc1)c1ccccn1

InChI Key InChIKey=IBMVKBJATBMJLP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264071   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50264071(CHEMBL452409 | N-(4-(pyridin-4-yl)thiazol-2-yl)pyr...)
Affinity DataIC50:  1.35E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50264071(CHEMBL452409 | N-(4-(pyridin-4-yl)thiazol-2-yl)pyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50264071(CHEMBL452409 | N-(4-(pyridin-4-yl)thiazol-2-yl)pyr...)
Affinity DataEC50:  1.64E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay