BDBM50264156 CHEMBL489167::N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-2-(1H-pyrrol-1-yl)benzamide

SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-n3cccc3)ccc2c1

InChI Key InChIKey=KRJJPCYIKDODRF-CLJLJLNGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264156   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50264156(CHEMBL489167 | N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)...)
Affinity DataIC50:  221nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed