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BDBM50265200 (2S)-2-amino-1-((S)-3-fluoropyrrolidin-1-yl)-2-(2-methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)ethanone::CHEMBL496131

SMILES: Cc1nc2CCC(Cc2s1)[C@H](N)C(=O)N1CC[C@H](F)C1

InChI Key: InChIKey=OKSKLVNFILAJLP-UXSKAQMCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265200   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50265200
PNG
((2S)-2-amino-1-((S)-3-fluoropyrrolidin-1-yl)-2-(2-...)
Show SMILES Cc1nc2CCC(Cc2s1)[C@H](N)C(=O)N1CC[C@H](F)C1
Show InChI InChI=1S/C14H20FN3OS/c1-8-17-11-3-2-9(6-12(11)20-8)13(16)14(19)18-5-4-10(15)7-18/h9-10,13H,2-7,16H2,1H3/t9?,10-,13-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 43n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human DPP4 expressed in baculovirus system


Eur J Med Chem 43: 1603-11 (2008)


Article DOI: 10.1016/j.ejmech.2007.11.014
BindingDB Entry DOI: 10.7270/Q2V69JCD
More data for this
Ligand-Target Pair