BDBM50265499 CHEMBL495534::N-[1-(1H-Imidazol-1-ylacetyl)piperidin-4-yl]-5-(phenylsulfonyl)-2-(trifluoromethyl)benzenesulfonamide

SMILES FC(F)(F)c1ccc(cc1S(=O)(=O)NC1CCN(CC1)C(=O)Cn1ccnc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=UEBXCNMAUOGYOC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265499   

TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265499(CHEMBL495534 | N-[1-(1H-Imidazol-1-ylacetyl)piperi...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265499(CHEMBL495534 | N-[1-(1H-Imidazol-1-ylacetyl)piperi...)
Affinity DataEC50:  230nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed