BDBM50265585 CHEMBL511077::N-[1-(1-Benzyl-L-prolyl)piperidin-4-yl]-5-(phenylsulfonyl)-2-(trifluoromethyl)benzenesulfonamide

SMILES FC(F)(F)c1ccc(cc1S(=O)(=O)NC1CCN(CC1)C(=O)[C@@H]1CCCN1Cc1ccccc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=SGJFKFRGJLVMQE-MHZLTWQESA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265585   

TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265585(CHEMBL511077 | N-[1-(1-Benzyl-L-prolyl)piperidin-4...)
Affinity DataIC50:  1.40E+3nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265585(CHEMBL511077 | N-[1-(1-Benzyl-L-prolyl)piperidin-4...)
Affinity DataEC50:  720nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed