BDBM50265743 4-Amino-6-(dimethylamino)-3-[6-(4-methylpiperazinyl)benzimidazol-2-yl]hydroquinolin-2-one::CHEMBL495529

SMILES CN(C)c1ccc2[nH]c(=O)c(-c3nc4ccc(cc4[nH]3)N3CCN(C)CC3)c(N)c2c1

InChI Key InChIKey=STYDJMQKMJBSLF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265743   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265743(4-Amino-6-(dimethylamino)-3-[6-(4-methylpiperaziny...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265743(4-Amino-6-(dimethylamino)-3-[6-(4-methylpiperaziny...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265743(4-Amino-6-(dimethylamino)-3-[6-(4-methylpiperaziny...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed