BDBM50265786 4-Amino-3-benzimidazol-2-yl-6-(4-methylpiperazinyl)hydroquinolin-2-one::CHEMBL457985

SMILES CN1CCN(CC1)c1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N)c2c1

InChI Key InChIKey=NZDKMYJOLQKUML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265786   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265786(4-Amino-3-benzimidazol-2-yl-6-(4-methylpiperazinyl...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265786(4-Amino-3-benzimidazol-2-yl-6-(4-methylpiperazinyl...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265786(4-Amino-3-benzimidazol-2-yl-6-(4-methylpiperazinyl...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed