BDBM50266555 CHEMBL457570::N-(3-(2-(dimethylamino)ethyl)-2-methyl-1H-inden-5-yl)naphthalene-2-sulfonamide

SMILES CN(C)CCC1=C(C)Cc2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12

InChI Key InChIKey=JIKAKDQZRABPAQ-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266555   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266555(CHEMBL457570 | N-(3-(2-(dimethylamino)ethyl)-2-met...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266555(CHEMBL457570 | N-(3-(2-(dimethylamino)ethyl)-2-met...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as stimulation of cAMP level after 30 mins by HTRF assay Inhibition of ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266555(CHEMBL457570 | N-(3-(2-(dimethylamino)ethyl)-2-met...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50266555(CHEMBL457570 | N-(3-(2-(dimethylamino)ethyl)-2-met...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed