BDBM50266575 CHEMBL4085777::US10323016, Example 14
SMILES COc1ccc(cc1)-n1c(SCc2c(F)cccc2F)ncc1N(C)c1ccc(OC)c(OC)c1
InChI Key InChIKey=JCKNYVPCZLTWCY-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50266575
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 7.70E+3nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
Affinity DataEC50: 939nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 7.75E+3nMAssay Description:Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 940nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair