BDBM50266580 CHEMBL4087611

SMILES N.N.COc1ccc(cc1OC)N(C)c1cnc(SCc2c(F)cc(OCCCN(CCS(O)(=O)=O)CCS(O)(=O)=O)cc2F)n1-c1ccc(F)cc1

InChI Key InChIKey=OLYFOLUROBNZLJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266580   

TargetG-protein coupled bile acid receptor 1(Mus musculus)
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50266580(CHEMBL4087611)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50266580(CHEMBL4087611)
Affinity DataEC50:  77nMAssay Description:Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed