BDBM50267403 CHEMBL477864::cyclopropyl(4-(2,5-dichlorophenylsulfonyl)piperazin-1-yl)methanone

SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

InChI Key InChIKey=NKGQEURLMKSCFY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267403   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267403(CHEMBL477864 | cyclopropyl(4-(2,5-dichlorophenylsu...)
Affinity DataEC50:  90nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267403(CHEMBL477864 | cyclopropyl(4-(2,5-dichlorophenylsu...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed