BDBM50267565 3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL522760

SMILES COc1cccc2c(coc12)C1=C(C(=O)NC1=O)c1cn(C)c2cc(Cl)c(F)cc12

InChI Key InChIKey=IATKMBHPUAENLP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50267565   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  6.16E+4nMAssay Description:Inhibition of CDK5/P35More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of CDK6/cyclin D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267565(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-...)
Affinity DataIC50:  5.95E+4nMAssay Description:Inhibition of CDK4/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed