BDBM50267719 2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9H-purin-2-ylamino)ethanol::CHEMBL519036

SMILES CC(C)n1cnc2c(nc(NCCO)nc12)N(C)c1cccc(Cl)c1

InChI Key InChIKey=BMUXNLKQMJEFGS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50267719   

TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent protein kinase PHO85(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Pho85 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase CAK1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Cak1 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMeiotic mRNA stability protein kinase SSN3(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Srb10 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase KIN28(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 Kin28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed