BDBM50267760 3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-indol-3-yl)pyrrole-2,5-dione::CHEMBL491647

SMILES COCc1cccc2c(cn(C)c12)C1=C(C(=O)NC1=O)c1coc2ccccc12

InChI Key InChIKey=HGBNXMUZCGQMOG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50267760   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of CDK5/P35More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  4.09E+3nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  3.88E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  8.33E+3nMAssay Description:Inhibition of CDK6/cyclin D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)
Affinity DataIC50:  8.62E+3nMAssay Description:Inhibition of CDK4/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed