BDBM50268024 CHEMBL4085336

SMILES Fc1ccc(NS(=O)(=O)c2cccc(Cl)c2)c(F)c1C#Cc1ccc2[nH]ncc2c1

InChI Key InChIKey=FSTCJQHCYNMFSY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268024   

TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50268024(CHEMBL4085336)
Affinity DataIC50:  994nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50268024(CHEMBL4085336)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type GST-tagged recombinant human full-length B-RAF expressed in baculovirus expression system using Ser/Thr3 as substrate after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed