BDBM50268238 CHEMBL4082728

SMILES Fc1ncc(Cn2c3ccccc3c(=O)[nH]c2=O)cc1NC(=O)[C@H]1CCN(Cc2ccncc2)C1

InChI Key InChIKey=CHRQYHKDXOIBPC-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268238   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268238(CHEMBL4082728)
Affinity DataIC50:  62nMAssay Description:Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268238(CHEMBL4082728)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant human PARP-2 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed