BDBM50268423 CHEMBL497202::N-(2-((1S,2R,4R)-4-(dimethylamino)-2-((4-(methylthio)phenylsulfonyl)methyl)cyclohexylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide
SMILES CSc1ccc(cc1)S(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)N(C)C
InChI Key InChIKey=ACJHGTKORBIIDI-NOXFTYBFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50268423
Affinity DataIC50: 0.370nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC by millipore filter plate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate reader assayMore data for this Ligand-Target Pair