BDBM50268784 (R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-indol-3-yl)-2-oxoacetamide::CHEMBL521901

SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)N[C@@H]3CCc4ccccc34)c2c1

InChI Key InChIKey=KFWPQIRBHBKYME-QGZVFWFLSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50268784   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268784((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha1beta2gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268784((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha2beta2gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Universita Di Pisa

Curated by ChEMBL
LigandPNGBDBM50268784((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha5beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50268784((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...)
Affinity DataKi:  95nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50268784((R)-N-(2,3-dihydro-1H-inden-1-yl)-2-(5-nitro-1H-in...)
Affinity DataKi:  1.96E+3nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed