BDBM50268879 CHEMBL4094717
SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CCCC1
InChI Key InChIKey=YBQHFHPOKHPBRB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50268879
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKd: 1.07E+3nMAssay Description:Binding affinity to human G9a in presence of SAM by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKd: 94nMAssay Description:Binding affinity to human GLP in presence of SAM by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Inhibition of human G9a catalytic domain (913 to 1193 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair