BDBM50269438 CHEMBL4076060

SMILES C[C@@H]1CN(CCN1c1nc(cc(=O)n1C)-c1ccncn1)c1ccc(F)cc1

InChI Key InChIKey=JNNSOGDGPPJJGF-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50269438   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269438(CHEMBL4076060)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269438(CHEMBL4076060)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269438(CHEMBL4076060)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human GSK-3beta using prephosphorylated-GS1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scintillation spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269438(CHEMBL4076060)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed