BDBM50269921 3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-quinuclidinol::CHEMBL478348

SMILES CCOC(=O)Cc1ccc(cc1)C#CC1(O)CN2CCC1CC2

InChI Key InChIKey=YWKVMGDEOUPQGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269921   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50:  970nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269921(3-[1'-{2'-(4''-Ethyl ethanoatephenyl)-ethynyl]-3-q...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21(DE3 pLysS) by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed