BDBM50269979 CHEMBL515170::r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-5-(trifluoromethyl)benzo[e][1,4]-oxazepin-2(1H,3H,5H)-one
SMILES CC[C@@H]1O[C@@](\C=C\C2CC2)(c2c(F)c(F)ccc2NC1=O)C(F)(F)F
InChI Key InChIKey=MSJCAWWJIHDUAU-OSTNNTLRSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50269979
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Antagonist activity at PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cells assessed as inhibition of parathyroid hormone (1...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of adrenergic alpha1D receptor (unknown origin)More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of adrenergic alpha2C receptor (unknown origin)More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.78E+3nMAssay Description:Antagonist activity at PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cells assessed as inhibition of DPC-AJ1951-induced cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of neurokinin 2 receptor (unknown origin)More data for this Ligand-Target Pair