BDBM50270471 CHEMBL4075556
SMILES Oc1cc(O)c(Cl)c(CCc2nccn2Cc2ccccc2)c1Cl
InChI Key InChIKey=VJODJXMSNZNVSM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50270471
Affinity DataKi: 440nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKd: 320nMAssay Description:Binding affinity to human N-terminal 6His-tagged HSP90alpha (1 to 236 residues) expressed in Escherichia coli BL21star/Rosetta2 (DE3) at 298 K by ITC...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair